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Menadione

 
 

Vitamin K3 or Menadione (2-Methyl-1, 4-naphthoquinone) is a parent compound for the whole group of Vitamin K and their derivatives. It is widely used in medicine (antihemorragic), and as nutritional supplement for animal and poultry feed.

Different derivatives of Menadione available are:

The water soluble form of Vitamin K3 is MSB (Sodium 2, 3-dihydro-2-mwthyl-1,4-naphthoquinone-2-sulfonate)

The other forms are different only in the cationic part of the molecule. The analogue contains a quaternary nitrogen cation group instead of the Na+ cation. They are MNBS and MPBS.

Uses:
Menadione (Vitamin K3) is especially important in certain species of animals, which are not able to produce Menadione in their metabolisms; poultry, pigs and aquatic animals. Demand for Menadione is growing annually, as livestock and animal production continues to grow worldwide.

Menadione Exhibit antihemorrnagic. When Vitamin K is low or lacking, the blood vessels rupture, causing excessive bleeding internally, petechial hemorrhagic in the liver and erosion of the gizzard may occur. Embryos from Vitamin deficient chickens have high mortality due to bleeding late in incubation. For prevention, supply adequate levels of Vitamin K in the feed and administer antibiotics and sulpha drugs with great care. (General requirement 5 to 7 grams per ton feed)

MENADIONE SODIUM BISULFITE (MSB)

CHEMICAL FEATURES:
Chemical Name : 1,2,3,4-Tetrahydro-2-methyl-1,4-dioxo-2- napthalenesulfonic acid sodium salt.

Molecular Formula : C 11 H 9 O 5 S.Na
Molecular Weight : 276.24
Structure :

SPECIFICATIONS:  

Description : White to pale white crystalline powder
Solubility : Freely soluble in water, slightly soluble in ethanol(96%) and in methanol Water by KF : Between 11.0 to 16.5%
Menadione : Between 51.4 to 55.0%
Assay (MSB) : Not less than 94.0% (dried substance)


USAGE:
Synthetic Vitamin K analogue and Blood coagulant

PACKING:
1Kg, 2Kg, 5Kg, 10Kg, 25Kg, 50Kg.

STORAGE:
Preserve in well-closed, light resistant containers

EXPIRY:
1 year from the date of production


Physical Properties
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MSDS
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MENADIONE NICOTINAMIDE BISULFITE (MNB 44%)

CHEMICAL FEATURES:
Chemical Name : 1,2,3,4-Tetrahydro-2-methyl-1,4-dioxonapthalen-2- sulfonic acid adduct with nicotin-3-amide.

Molecular Formula : C 17 H 16 O 6 N 2 S
Molecular Weight : 376.24
Structure :

SPECIFICATIONS:

Description : A White to pale white crystalline powder
Solubility : Insoluble in Water
Water by KF : Not More than 1.0%
Menadione : Not Less than 43.7%
Nicotinamide : Not Less than 31.0%

USAGE : Synthetic Vitamin K analogue and Blood coagulant

PACKING : 1Kg, 2Kg, 5Kg, 10Kg, 25Kg, 50Kg.

STORAGE : Preserve in well-closed, light resistant containers

EXPIRY : 3 years from the date of production


Physical Properties
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MSDS
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MENADIONE DIMETHYLPYRIMIDINOL BISULFITE (MPB 44%)

CHEMICAL FEATURES:

Chemical Name : 2 ? methyl -1,4 ? napthoquinone 2-hydroxy ? 4,6 ? dimethylpyrimidine bisulfite
Molecular Formula : C 17 H 18 O 6 N 2 S
Molecular Weight : 378.40
Structure :

 

SPECIFICATIONS:  

Description : A White to pale white crystalline powder.
Solubility : Insoluble in Water.
Water by KF : Not More than 2.0%.
Menadione : Not Less than 44.0%.

USAGE : Synthetic Vitamin ?K? analogue and Blood coagulant.

PACKING : 1Kg, 2Kg, 5Kg, 10Kg, 25Kg, 50Kg.

STORAGE : Preserve in well-closed, light resistant containers.

EXPIRY : 3 years from the date of production.

Physical Properties
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MSDS
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